Suppose a eukaryotic RNA molecule has no 5′ cap. Will this molecule be translated?
a)Yes, but in small quantities
b)Yes, just like it always did.
c)Yes, but the cell will provide an excess of GTP
Smooth muscle and skeletal muscle have different forms of mRNA due to … :
c) Alternative splicing
d)The degeneration of mRNA fragments
A precursor messenger RNA (pre-mRNA) is …
A. Only in prokaryotes.
B. In prokaryotes and eukaryotes.
C.Only in the eukaryotic nucleus.
D. Only in the cytoplasm of eukaryotes.
Following the repair of base mismatch endonuclease, ____________ is (are) required to complete the repair.
A. DNA polymerase
B. DNA polymerase and ligase
C. Primase, DNA polymerase and ligase .
D. Primase and ligase
Imagine that a genetic mutation makes the primase unable to make RNA primers. Assuming all other enzymes required for DNA replication working well, what (s) phase (s) of DNA replication you expect anyway to see in these mutant cells?
A. Both directors and discontinuous strands are synthesized but Okazaki fragments would never be linked.
B.None of the steps in the replication could not take place.
C. The double-stranded DNA could be unwound by helicase, but none of the two strands would be replicated.
D. The director would be synthesized strand but not the discontinuous strand.
At the beginning of the translation, initiator tRNA mates in a complementary manner with the start codon of _______ ribosome.
A. Site A first, then the P site
B. Site A first, then E Site
C. Site A
D. P Site
In prokaryotes, which of the expression of the following genes control modes will not happen?
A. Enabling developers
B. The chromatin remodeling
C. The protein degradation rate
D.The mRNA degradation rate
In the experience of Hershey and Chase, 32P was used to label ________ while the 35S was used to label __________.
A. The DNA;
The RNA; the protein
C. Proteins; DNA
D. Proteins; phospholipids
Among the nucleotide sequences listed below, which represents the sequence complementary to the sequence 5′-GACGTT-3 ‘?
A: TCATGG 5′-3 ‘
B.CTGCAA 3′-5 ‘
C.AGTACC 3′-5 ‘
D.TCATGG 3′-5 ‘
The delivery of proteins to their final destination in eukaryotic cells is …
A.Directed by signals part of protein
C.Based on the transcription factors.
D.Controlled by the type of ribosome used.
What happens when the live strain (R) non-pathogenic Streptococcus pneumoniae is mixed with bacteria pathogenic strain (S) heat-killed?
A:S strain of bacteria is transformed into strain R
B:R strain of bacteria is transformed into strain S
C: S strain of bacteria back to life.
D. R strain of bacteria is killed and the S strain remains dead.
During normal DNA replication, a portion of the DNA 3 ‘ends of a linear chromosome is not copied in the new DNA strands because …
A. Cells do not require the DNA at the ends of chromosomes.
B. The RNA primers at the beginning of a new strand can not be replaced by DNA.
C. These ends are of the Okazaki fragments that are lost.
D. The DNA ligase can join the fragments on chromosome terminations.
During translation, tRNA bind to mRNA using … A. Non-polar covalent bonds
B. Hydrogen bonds
C. Ionic bonds
D. Van der Waals forces
What direction is the polymerization of DNA during replication?
A: The 5 ‘→ 3’ strand Director and 3 ‘→ 5’ to the discontinuous strand.
B:In the 5 ‘→ 3’ only.
C.In the 3 ‘→ 5’ strand for the director and 5 ‘→ 3’ to the discontinuous strand.
D. Or 3 ‘→ 5’ or 5 ‘→ 3’ to the strands, all depending on the origin of replication.
In eukaryotes, genes coding for proteins are transcribed by …
A.RNA polymerase III.
B.RNA polymerase II.
C.The RNA polymerase I or III.
D.RNA polymerase I.
The termination of transcription in prokaryotes requires …
A. stop codon.
C.A poly-A sequence
D.A terminator sequence.
What is the function of a poly-A 3 ‘sequence of a eukaryotic mRNA?
A:Termination of transcription
B. Intron splice signal.
C.Site initial ribosome attachment.
D.Protection against cytosolic enzymes.
During replication of DNA, which of the following enzymes adds nucleotides to the 3 ‘end of an existing strand to construct a new DNA strand?
A. DNA polymerase
In eukaryotes, translation of the genes encoding for nuclear proteins is in …
C.The Golgi apparatus
Post-translational modifications include ….
A:The exchange of an amino acid encoded by an amino acid codon of RNA encoded by a DNA codon.
B.Chemical modifications of proteins.
C.Cleavage of the poly-A tail of the mRNA.
D.The chromatin remodeling.
The formation of a peptide bond during translation is catalyzed by …
A:The pRNPn (small nuclear ribonucleoprotein) B.RNA polymerase
C.The aminoacyl-tRNA transferase
Adjacent nucleotides on one strand of DNA are joined together by a (e) … .
A: Phosphodiester bond
B.A peptide link
“Alphabet” RNA used in the genetic code ____ letters.
During replication of DNA ligase is active on the discontinuous strand. Why?
A:Discontinuous strand is synthesized more slowly, and DNA ligase accelerates the polymerization rate of the DNA polymerase.
B.DNA is synthesized in the 3 ‘→ 5’ on the discontinuous strand.
C.The discontinuous strand, the ligase must bind the RNA primer with Okazaki fragment.
D.Discontinuous strand contains more DNA segments smaller than the director strand, such short segments are connected together by DNA ligase.
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